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A review on the ethnomedicinal uses, phytochemistry and pharmacology of Alpinia officinarum Hance.

Identifieur interne : 000464 ( Main/Exploration ); précédent : 000463; suivant : 000465

A review on the ethnomedicinal uses, phytochemistry and pharmacology of Alpinia officinarum Hance.

Auteurs : Ibrahim Babangida Abubakar [Nigeria] ; Ibrahim Malami [Nigeria] ; Yakubu Yahaya [Nigeria] ; Sahabi Manga Sule [Nigeria]

Source :

RBID : pubmed:29803568

Descripteurs français

English descriptors

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE

Alpinia officinarum Hance is a perennial plant that has been traditionally used for many decades to treat several ailments including inflammation, pain, stomach-ache, cold, amongst others. Pharmacological studies over the years have demonstrated remarkable bioactivities that could be further explored for development of new therapeutic agents against various ailments.

AIM OF THE STUDY

The paper critically reviewed the ethno-medicinal uses, pharmacology, and phytochemistry of A. officinarum.

METHODS

Keywords including A. officinarum and its synonyms were searched using electronic databases including ISI web of knowledge, Science direct, Scopus, PubMed, Google scholar and relevant database for Masters and Doctoral theses.

RESULTS

A. officinarum is prepared in Asia, Turkey, Morocco and Iran as a decoction, infusion or juice as a single preparation or in combination with other herbs, food or drinks for the treatment of general health problems including cold, inflammation, digestive disorders, etc. Pharmacological studies revealed the potent in vitro and in vivo bioactivities of various parts of A. officinarum that include anti-inflammatory, cytotoxicity, homeostasis, lipid regulation, antioxidant, antiviral, antimicrobial, antiosteoporosis, etc. Over 90 phytochemical constituents have been identified and isolated from A. officinarum comprising vastly of phenolic compounds especially diarylheptanoids isolated from the rhizome and considered the most active bioactive components.

CONCLUSION

In vitro and in vivo studies have confirmed the potency of A. officinarum. However, further studies are required to establish the mechanisms mediating its bioactivities in relation to the medicinal uses as well as investigating any potential toxicity for future clinical studies.


DOI: 10.1016/j.jep.2018.05.027
PubMed: 29803568


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">
<p>
<b>ETHNOPHARMACOLOGICAL RELEVANCE</b>
</p>
<p>Alpinia officinarum Hance is a perennial plant that has been traditionally used for many decades to treat several ailments including inflammation, pain, stomach-ache, cold, amongst others. Pharmacological studies over the years have demonstrated remarkable bioactivities that could be further explored for development of new therapeutic agents against various ailments.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>AIM OF THE STUDY</b>
</p>
<p>The paper critically reviewed the ethno-medicinal uses, pharmacology, and phytochemistry of A. officinarum.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHODS</b>
</p>
<p>Keywords including A. officinarum and its synonyms were searched using electronic databases including ISI web of knowledge, Science direct, Scopus, PubMed, Google scholar and relevant database for Masters and Doctoral theses.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>A. officinarum is prepared in Asia, Turkey, Morocco and Iran as a decoction, infusion or juice as a single preparation or in combination with other herbs, food or drinks for the treatment of general health problems including cold, inflammation, digestive disorders, etc. Pharmacological studies revealed the potent in vitro and in vivo bioactivities of various parts of A. officinarum that include anti-inflammatory, cytotoxicity, homeostasis, lipid regulation, antioxidant, antiviral, antimicrobial, antiosteoporosis, etc. Over 90 phytochemical constituents have been identified and isolated from A. officinarum comprising vastly of phenolic compounds especially diarylheptanoids isolated from the rhizome and considered the most active bioactive components.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>CONCLUSION</b>
</p>
<p>In vitro and in vivo studies have confirmed the potency of A. officinarum. However, further studies are required to establish the mechanisms mediating its bioactivities in relation to the medicinal uses as well as investigating any potential toxicity for future clinical studies.</p>
</div>
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